Elizabeth Holmes – $ 4.5 Billion

Elizabeth Holmes is one of the self-made female billionaires on this list. This American entrepreneur worked hard to gain her billionaire status which also led her to be considered as one of the most influential women in the world. Elizabeth is the founder and inventor of Theranos, a company that has revolutionized blood testing and how blood is taken.

Because of this business venture, she gained a net worth of $4.5 billion. Unfortunately, she had to call a bankruptcy attorney after the reliability of her company was questioned. She lost billions and her blood-test company has now become defunct.